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The role of metabotropic glutamate receptor 5 in the pathogenesis of mood disorders and addiction: combining preclinical evidence with human Positron Emission Tomography (PET) studies

In the present review, we deliver an overview of the involvement of metabotropic glutamate receptor 5 (mGluR5) activity and density in pathological anxiety, mood disorders and addiction. Specifically, we will describe mGluR5 studies in humans that employed Positron Emission Tomography (PET) and comb...

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Detalles Bibliográficos
Publicado en:Front Neurosci
Main Authors: Terbeck, Sylvia, Akkus, Funda, Chesterman, Laurence P., Hasler, Gregor
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364244/
https://ncbi.nlm.nih.gov/pubmed/25852460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00086
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