Oxytocin prevents ethanol actions at δ subunit-containing GABA(A) receptors and attenuates ethanol-induced motor impairment in rats

Even moderate doses of alcohol cause considerable impairment of motor coordination, an effect that substantially involves potentiation of GABAergic activity at δ subunit-containing GABA(A) receptors (δ-GABA(A)Rs). Here, we demonstrate that oxytocin selectively attenuates ethanol-induced motor impair...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bowen, Michael T., Peters, Sebastian T., Absalom, Nathan, Chebib, Mary, Neumann, Inga D., McGregor, Iain S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364242/
https://ncbi.nlm.nih.gov/pubmed/25713389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416900112
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