Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells

The immune mechanisms regulating epithelial cell repair after injury remain poorly defined. We demonstrate here that lymphotoxin beta receptor (LTβR) signaling in intestinal epithelial cells promotes self-repair after mucosal damage. Using a conditional gene-targeted approach, we demonstrate that LT...

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Bibliografiska uppgifter
I publikationen:Mucosal Immunol
Huvudupphovsmän: Macho-Fernandez, Elise, Koroleva, Ekaterina P., Spencer, Cody M., Tighe, Michael, Torrado, Egidio, Cooper, Andrea M., Fu, Yang-Xin, Tumanov, Alexei V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364000/
https://ncbi.nlm.nih.gov/pubmed/25183367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.78
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