Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells

The immune mechanisms regulating epithelial cell repair after injury remain poorly defined. We demonstrate here that lymphotoxin beta receptor (LTβR) signaling in intestinal epithelial cells promotes self-repair after mucosal damage. Using a conditional gene-targeted approach, we demonstrate that LT...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Macho-Fernandez, Elise, Koroleva, Ekaterina P., Spencer, Cody M., Tighe, Michael, Torrado, Egidio, Cooper, Andrea M., Fu, Yang-Xin, Tumanov, Alexei V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364000/
https://ncbi.nlm.nih.gov/pubmed/25183367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.78
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