Focal adhesion kinase-mediated activation of glycogen synthase kinase 3β regulates IL-33 receptor internalization and IL-33 signaling

IL-33, a relatively new member of the IL-1 cytokine family, plays a crucial role in allergic inflammation and acute lung injury. ST2L, the receptor for IL-33, is expressed on immune effector cells and lung epithelia, and plays a critical role in triggering inflammation. We have previously shown that...

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Veröffentlicht in:J Immunol
Hauptverfasser: Zhao, Jing, Wei, Jianxin, Bowser, Rachel K, Traister, Russell S, Fan, Ming-Hui, Zhao, Yutong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363995/
https://ncbi.nlm.nih.gov/pubmed/25472995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401414
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