Glycogen Synthase Kinase 3 and h-prune Regulate Cell Migration by Modulating Focal Adhesions

h-prune, which has been suggested to be involved in cell migration, was identified as a glycogen synthase kinase 3 (GSK-3)-binding protein. Treatment of cultured cells with GSK-3 inhibitors or small interfering RNA (siRNA) for GSK-3 and h-prune inhibited their motility. The kinase activity of GSK-3...

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Bibliographische Detailangaben
Hauptverfasser: Kobayashi, Tsuyoshi, Hino, Shin-ichiro, Oue, Naohide, Asahara, Toshimasa, Zollo, Massimo, Yasui, Wataru, Kikuchi, Akira
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347031/
https://ncbi.nlm.nih.gov/pubmed/16428445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.898-911.2006
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