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Claudin-2 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Claudin-2 Independently Determines the Leaky Property of Tight Junctions in MDCK Cells

Tight junctions (TJs) regulate the movements of substances through the paracellular pathway, and claudins are major determinants of TJ permeability. Claudin-2 forms high conductive cation pores in TJs. The suppression of claudin-2 expression by RNA interference in Madin-Darby canine kidney (MDCK) II...

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Foilsithe in:PLoS One
Main Authors: Tokuda, Shinsaku, Furuse, Mikio
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363821/
https://ncbi.nlm.nih.gov/pubmed/25781928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119869
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