Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity

Tight junctions (TJs) establish the epithelial barrier and are thought to form a membrane fence to regulate epithelial polarity, although the roles of TJs in epithelial polarity remain controversial. Claudins constitute TJ strands in conjunction with the cytoplasmic scaffolds ZO-1 and ZO-2 and play...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Otani, Tetsuhisa, Nguyen, Thanh Phuong, Tokuda, Shinsaku, Sugihara, Kei, Sugawara, Taichi, Furuse, Kyoko, Miura, Takashi, Ebnet, Klaus, Furuse, Mikio
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781433/
https://ncbi.nlm.nih.gov/pubmed/31467165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812157
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