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Evaluating LRRK2 Genetic Variants with Unclear Pathogenicity

Mutations in the leucine-rich repeat kinase 2 (LRRK2) have been known to be a major genetic component affecting Parkinson's disease (PD). However, the pathogenicity of many of the LRRK2 variants is unclear because they have been detected in single patients or also in patients and controls. Here...

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Podrobná bibliografie
Vydáno v:Biomed Res Int
Hlavní autoři: Refai, Fathima Shaffra, Ng, Shin Hui, Tan, Eng-King
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363499/
https://ncbi.nlm.nih.gov/pubmed/25821816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/678701
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