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Evaluating LRRK2 Genetic Variants with Unclear Pathogenicity

Mutations in the leucine-rich repeat kinase 2 (LRRK2) have been known to be a major genetic component affecting Parkinson's disease (PD). However, the pathogenicity of many of the LRRK2 variants is unclear because they have been detected in single patients or also in patients and controls. Here...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Refai, Fathima Shaffra, Ng, Shin Hui, Tan, Eng-King
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363499/
https://ncbi.nlm.nih.gov/pubmed/25821816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/678701
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