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Patterns of Linkage Disequilibrium of LRRK2 across Different Races: Implications for Genetic Association Studies

Genome Wide Association Studies (GWASs) have identified trait-associated polymorphisms via a hypothesis-free approach. However, it is challenging when attempting to reproduce GWAS findings in different populations as it fundamentally relies on the similar patterns of linkage disequilibrium (LD) betw...

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Detalhes bibliográficos
Main Authors: Li, Huihua, Teo, Yik Ying, Tan, Eng King
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764133/
https://ncbi.nlm.nih.gov/pubmed/24040382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075041
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