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Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of Acidic Fibroblast Growth Factor
Fibroblast growth factor 1 (FGF1) is a heparin-binding proangiogenic protein. FGF1 lacks the conventional N-terminal signal peptide required for secretion through the endoplasmic reticulum (ER) -Golgi secretory pathway. FGF1 is released through a Cu(2+) - mediated nonclassical secretion pathway. The...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362929/ https://ncbi.nlm.nih.gov/pubmed/25224745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2014.09.008 |
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