NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I—relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1)

Human fibroblast growth factor (hFGF-1) is a ~17 kDa heparin binding cytokine. It lacks the conventional hydrophobic N-terminal signal sequence and is secreted through non-classical secretion routes. Under stress, hFGF-1 is released as a multiprotein complex consisting of hFGF-1, S100A13 (a calcium...

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Detalhes bibliográficos
Main Authors: Kathir, Karuppanan Muthusamy, Gao, Li, Rajalingam, Dakshinamurthy, Daily, Anna E., Brixey, Sherri, Liu, Huimin, Davis, Dan, Adams, Paul, Prudovsky, Igor, Kumar, Thallapuranam Krishnaswamy Suresh
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628535/
https://ncbi.nlm.nih.gov/pubmed/19835837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.09.024
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