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Making connections: Insulators organize eukaryotic chromosomes into independent cis-regulatory networks

Insulators play a central role in subdividing the chromosome into a series of discrete topologically independent domains and in ensuring that enhancers and silencers contact their appropriate target genes. In this review we first discuss the general characteristics of insulator elements and their as...

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Bibliografische gegevens
Gepubliceerd in:Bioessays
Hoofdauteurs: Chetverina, Darya, Aoki, Tsutomu, Erokhin, Maksim, Georgiev, Pavel, Schedl, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362772/
https://ncbi.nlm.nih.gov/pubmed/24277632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300125
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