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Making connections: Insulators organize eukaryotic chromosomes into independent cis-regulatory networks
Insulators play a central role in subdividing the chromosome into a series of discrete topologically independent domains and in ensuring that enhancers and silencers contact their appropriate target genes. In this review we first discuss the general characteristics of insulator elements and their as...
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| Pubblicato in: | Bioessays |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362772/ https://ncbi.nlm.nih.gov/pubmed/24277632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300125 |
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