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Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development of polycystic liver diseases
OBJECTIVE: Polycystic liver diseases (PCLDs) are genetic disorders characterised by progressive bile duct dilatation and/or cyst development. Their pathogenesis is a consequence of hyperproliferation, hypersecretion and microRNA alterations in cholangiocytes. Here we evaluate the role of matrix meta...
Kaydedildi:
| Yayımlandı: | Gut |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362729/ https://ncbi.nlm.nih.gov/pubmed/24436140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305281 |
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