Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine()

Chemokines and their receptors control cell migration during development, immune system responses, and in numerous diseases including inflammation and cancer. The structural basis of receptor:chemokine recognition has been a long-standing unanswered question due to the challenges of structure determ...

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Veröffentlicht in:Science
Hauptverfasser: Qin, Ling, Kufareva, Irina, Holden, Lauren G., Wang, Chong, Zheng, Yi, Zhao, Chunxia, Fenalti, Gustavo, Wu, Huixian, Han, Gye Won, Cherezov, Vadim, Abagyan, Ruben, Stevens, Raymond C., Handel, Tracy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362693/
https://ncbi.nlm.nih.gov/pubmed/25612609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1261064
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