DNA methylation of apoptosis genes in rectal cancer predicts patient survival and tumor recurrence

Deregulation of the apoptotic pathway, one of the hallmarks of tumor growth and -progression, has been shown to have prognostic value for tumor recurrence in rectal cancer. In order to develop clinically relevant bio-markers, we studied the methylation status of promoter regions of key apoptosis gen...

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Dettagli Bibliografici
Pubblicato in:Apoptosis
Autori principali: Benard, Anne, Zeestraten, Eliane C. M., Goossens-Beumer, Inès J., Putter, Hein, van de Velde, Cornelis J. H., Hoon, Dave S. B., Kuppen, Peter J. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362525/
https://ncbi.nlm.nih.gov/pubmed/25064172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-014-1022-z
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