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Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
Alopecia areata (AA) is a common autoimmune disease resulting from damage of the hair follicle by T cells. The immune pathways required for autoreactive T cell activation in AA are not defined limiting clinical development of rational targeted therapies(1). Genome-wide association studies (GWAS)(2)...
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| Опубликовано в: : | Nat Med |
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| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362521/ https://ncbi.nlm.nih.gov/pubmed/25129481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3645 |
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