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CXCR3 Blockade Inhibits T-cell Migration into the Skin and Prevents Development of Alopecia Areata

Alopecia areata (AA) is an autoimmune disease of the hair follicle (HF) that results in hair loss of varying severity. Recently, we showed that IFN-γ-producing NKG2D(+)CD8(+) T cells actively infiltrate the HF, and are responsible for its destruction in C3H/HeJ AA mice. Our transcriptional profiling...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Dai, Zhenpeng, Xing, Luzhou, Cerise, Jane, Wang, Eddy Hsi Chun, Jabbari, Ali, de Jong, Annemieke, Petukhova, Lynn, Christiano, Angela M., Clynes, Raphael
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031416/
https://ncbi.nlm.nih.gov/pubmed/27412416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501798
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