The adenovirus E1A oncoprotein N-terminal transcriptional repression domain enhances p300 autoacetylation and inhibits histone H3 Lys18 acetylation

Expression of the adenovirus E1A N-terminal transcription repression domain alone (E1A 1-80) represses transcription from specific promoters such as HER2 [1] and from reconstituted chromatin [2]. Significantly, E1A 1-80 can induce the death of human breast cancer cells over-expressing the HER2 oncog...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes Cancer
Main Authors: Zhao, Ling-Jun, Loewenstein, Paul M., Green, Maurice
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362482/
https://ncbi.nlm.nih.gov/pubmed/25821559
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