Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation

The intracellular protein HMGB1 is released from cells and acts as a damage-associated molecular pattern molecule during many diseases, including inflammatory bowel disease (IBD); however, the intracellular function of HMGB1 during inflammation is poorly understood. Here, we demonstrated that cytoso...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhu, Xiaorong, Messer, Jeannette S., Wang, Yunwei, Lin, Fanfei, Cham, Candace M., Chang, Jonathan, Billiar, Timothy R., Lotze, Michael T., Boone, David L., Chang, Eugene B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362239/
https://ncbi.nlm.nih.gov/pubmed/25642769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76344
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