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Musashi2 sustains the mixed-lineage leukemia–driven stem cell regulatory program

Leukemia stem cells (LSCs) are found in most aggressive myeloid diseases and contribute to therapeutic resistance. Leukemia cells exhibit a dysregulated developmental program as the result of genetic and epigenetic alterations. Overexpression of the RNA-binding protein Musashi2 (MSI2) has been previ...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Park, Sun-Mi, Gönen, Mithat, Vu, Ly, Minuesa, Gerard, Tivnan, Patrick, Barlowe, Trevor S., Taggart, James, Lu, Yuheng, Deering, Raquel P., Hacohen, Nir, Figueroa, Maria E., Paietta, Elisabeth, Fernandez, Hugo F., Tallman, Martin S., Melnick, Ari, Levine, Ross, Leslie, Christina, Lengner, Christopher J., Kharas, Michael G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362230/
https://ncbi.nlm.nih.gov/pubmed/25664853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78440
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