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Musashi2 sustains the mixed-lineage leukemia–driven stem cell regulatory program
Leukemia stem cells (LSCs) are found in most aggressive myeloid diseases and contribute to therapeutic resistance. Leukemia cells exhibit a dysregulated developmental program as the result of genetic and epigenetic alterations. Overexpression of the RNA-binding protein Musashi2 (MSI2) has been previ...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Clin Invest |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362230/ https://ncbi.nlm.nih.gov/pubmed/25664853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78440 |
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