The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes

Appropriate nutrient response is essential for growth and reproduction. Under favorable nutrient conditions, the C. elegans nuclear receptor DAF-12 is activated by dafachronic acids, hormones that commit larvae to reproductive growth. Here, we report that in addition to its well-studied role in cont...

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Gepubliceerd in:PLoS Genet
Hoofdauteurs: Wang, Zhu, Stoltzfus, Jonathan, You, Young-jai, Ranjit, Najju, Tang, Hao, Xie, Yang, Lok, James B., Mangelsdorf, David J., Kliewer, Steven A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361679/
https://ncbi.nlm.nih.gov/pubmed/25774872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005027
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