Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes

Nematode parasitism is a worldwide health problem resulting in malnutrition and morbidity in over 1 billion people. The molecular mechanisms governing infection are poorly understood. Here, we report that an evolutionarily conserved nuclear hormone receptor signaling pathway governs development of t...

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Bibliografski detalji
Glavni autori: Wang, Zhu, Zhou, X. Edward, Motola, Daniel L., Gao, Xin, Suino-Powell, Kelly, Conneely, Aoife, Ogata, Craig, Sharma, Kamalesh K., Auchus, Richard J., Lok, James B., Hawdon, John M., Kliewer, Steven A., Xu, H. Eric, Mangelsdorf, David J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695123/
https://ncbi.nlm.nih.gov/pubmed/19497877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904064106
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