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Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasite Strongyloides stercoralis

DAF-12 is nematode-specific nuclear receptor that has been proposed to govern development of the infectious stage of parasitic species, including Strongyloides stercoralis. Here, we identified a parasite-specific coactivator, called DAF-12 interacting protein-1 (DIP-1), that is required for DAF-12 l...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cheong, Mi Cheong, Wang, Zhu, Jaleta, Tegegn G., Li, Xinshe, Lok, James B., Kliewer, Steven A., Mangelsdorf, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923533/
https://ncbi.nlm.nih.gov/pubmed/33602820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021864118
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