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The nuclear receptor DAF-12 regulates nutrient metabolism and reproductive growth in nematodes.

Appropriate nutrient response is essential for growth and reproduction. Under favorable nutrient conditions, the C. elegans nuclear receptor DAF-12 is activated by dafachronic acids, hormones that commit larvae to reproductive growth. Here, we report that in addition to its well-studied role in cont...

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Bibliografische gegevens
Hoofdauteurs: Zhu Wang, Jonathan Stoltzfus, Young-Jai You, Najju Ranjit, Hao Tang, Yang Xie, James B Lok, David J Mangelsdorf, Steven A Kliewer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2015-03-01
Reeks:PLoS Genetics
Online toegang:http://europepmc.org/articles/PMC4361679?pdf=render
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