A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication

Hepatitis C virus (HCV) infection is a leading cause of liver disease worldwide. The HCV RNA genome is translated into a single polyprotein. Most of the cleavage sites in the non-structural (NS) polyprotein region are processed by the NS3/NS4A serine protease. The vital NS2-NS3 cleavage is catalyzed...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Isken, Olaf, Langerwisch, Ulrike, Jirasko, Vlastimil, Rehders, Dirk, Redecke, Lars, Ramanathan, Harish, Lindenbach, Brett D., Bartenschlager, Ralf, Tautz, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361677/
https://ncbi.nlm.nih.gov/pubmed/25774920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004736
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados