Functional Characterization of Bovine Viral Diarrhea Virus Nonstructural Protein 5A by Reverse Genetic Analysis and Live Cell Imaging

Nonstructural protein 5A (NS5A) of bovine viral diarrhea virus (BVDV) is a hydrophilic phosphoprotein with RNA binding activity and a critical component of the viral replicase. In silico analysis suggests that NS5A encompasses three domains interconnected by two low-complexity sequences (LCSs). Whil...

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Detalhes bibliográficos
Main Authors: Isken, Olaf, Langerwisch, Ulrike, Schönherr, Robert, Lamp, Benjamin, Schröder, Kristin, Duden, Rainer, Rümenapf, Tillmann H., Tautz, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911689/
https://ncbi.nlm.nih.gov/pubmed/24131714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01957-13
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