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Simultaneous detection of 19 K-ras mutations by free-solution conjugate electrophoresis of ligase detection reaction products on glass microchips

We demonstrate here the power and flexibility of free-solution conjugate electrophoresis (FSCE) as a method of separating DNA fragments by electrophoresis with no sieving polymer network. Previous work introduced the coupling of FSCE with ligase detection reaction (LDR) to detect point mutations, ev...

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Dettagli Bibliografici
Pubblicato in:Electrophoresis
Autori principali: Albrecht, Jennifer Coyne, Kotani, Akira, Lin, Jennifer S., Soper, Steven A., Barron, Annelise E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361093/
https://ncbi.nlm.nih.gov/pubmed/23192597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201200462
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