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A 265-base DNA sequencing read by capillary electrophoresis with no separation matrix

Electrophoretic DNA sequencing without a polymer matrix is currently possible only with the use of some kind of “drag-tag” as a mobility modifier. In Free-Solution Conjugate Electrophoresis (FSCE), a drag-tag attached to each DNA fragment breaks linear charge-to-friction scaling, enabling size-based...

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Detalhes bibliográficos
Main Authors: Albrecht, Jennifer Coyne, Lin, Jennifer S., Barron, Annelise E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271724/
https://ncbi.nlm.nih.gov/pubmed/21182303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac102188p
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