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Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function

Translation initiation in the hepatitis C virus (HCV) occurs through a cap-independent mechanism that involves an internal ribosome entry site (IRES) capable of interacting with and utilizing the eukaryotic translational machinery. In this review, we focus on the structural configuration of the diff...

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Bibliografiske detaljer
Udgivet i:Wiley Interdiscip Rev RNA
Main Authors: Khawaja, Anas, Vopalensky, Vaclav, Pospisek, Martin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361049/
https://ncbi.nlm.nih.gov/pubmed/25352252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1268
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