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Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function

Translation initiation in the hepatitis C virus (HCV) occurs through a cap-independent mechanism that involves an internal ribosome entry site (IRES) capable of interacting with and utilizing the eukaryotic translational machinery. In this review, we focus on the structural configuration of the diff...

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Detalhes bibliográficos
Publicado no:Wiley Interdiscip Rev RNA
Main Authors: Khawaja, Anas, Vopalensky, Vaclav, Pospisek, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361049/
https://ncbi.nlm.nih.gov/pubmed/25352252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1268
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