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Hepatitis C Virus Translation Inhibitors Targeting the Internal Ribosomal Entry Site
The internal ribosome entry site (IRES) in the 5′ untranslated region (UTR) of the hepatitis C virus (HCV) genome initiates translation of the viral polyprotein precursor. The unique structure and high sequence conservation of the 5′ UTR render the IRES RNA a potential target for the development of...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954896/ https://ncbi.nlm.nih.gov/pubmed/24138284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401312n |
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