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Screening for inhibitors of the hepatitis C virus internal ribosome entry site RNA

The highly conserved internal ribosome entry site (IRES) of hepatitis C virus (HCV) regulates translation of the viral RNA genome and is essential for the expression of HCV proteins in infected host cells. The structured subdomain IIa of the IRES element is the target site of recently discovered ben...

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Hlavní autoři: Zhou, Shou, Rynearson, Kevin D., Ding, Kejia, Brunn, Nicholas D., Hermann, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758467/
https://ncbi.nlm.nih.gov/pubmed/23602522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.03.054
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