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Screening for inhibitors of the hepatitis C virus internal ribosome entry site RNA

The highly conserved internal ribosome entry site (IRES) of hepatitis C virus (HCV) regulates translation of the viral RNA genome and is essential for the expression of HCV proteins in infected host cells. The structured subdomain IIa of the IRES element is the target site of recently discovered ben...

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Bibliographic Details
Main Authors: Zhou, Shou, Rynearson, Kevin D., Ding, Kejia, Brunn, Nicholas D., Hermann, Thomas
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758467/
https://ncbi.nlm.nih.gov/pubmed/23602522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.03.054
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