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Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9

Loss of neurons that express the neuropeptide hypocretin (Hcrt) has been implicated in narcolepsy, a debilitating disorder characterized by excessive daytime sleepiness and cataplexy. Cell replacement therapy, using Hcrt-expressing neurons generated in vitro, is a potentially useful therapeutic appr...

詳細記述

保存先:
書誌詳細
出版年:Development
主要な著者: Liu, Justin, Merkle, Florian T., Gandhi, Avni V., Gagnon, James A., Woods, Ian G., Chiu, Cindy N., Shimogori, Tomomi, Schier, Alexander F., Prober, David A.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360184/
https://ncbi.nlm.nih.gov/pubmed/25725064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117424
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