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Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9
Loss of neurons that express the neuropeptide hypocretin (Hcrt) has been implicated in narcolepsy, a debilitating disorder characterized by excessive daytime sleepiness and cataplexy. Cell replacement therapy, using Hcrt-expressing neurons generated in vitro, is a potentially useful therapeutic appr...
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| Publicado no: | Development |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360184/ https://ncbi.nlm.nih.gov/pubmed/25725064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117424 |
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