Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ

[Image: see text] The bacterial cell division protein FtsZ is one of many potential targets for the development of novel antibiotics. Recently, zantrin Z3 was shown to be a cross-species inhibitor of FtsZ; however, its specific interactions with the protein are still unknown. Herein we report the sy...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:ACS Med Chem Lett
Autors principals: Nepomuceno, Gabriella M., Chan, Katie M., Huynh, Valerie, Martin, Kevin S., Moore, Jared T., O’Brien, Terrence E., Pollo, Luiz A. E., Sarabia, Francisco J., Tadeus, Clarissa, Yao, Zi, Anderson, David E., Ames, James B., Shaw, Jared T.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360151/
https://ncbi.nlm.nih.gov/pubmed/25815151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500497s
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars