Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ

[Image: see text] The bacterial cell division protein FtsZ is one of many potential targets for the development of novel antibiotics. Recently, zantrin Z3 was shown to be a cross-species inhibitor of FtsZ; however, its specific interactions with the protein are still unknown. Herein we report the sy...

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Argitaratua izan da:ACS Med Chem Lett
Egile Nagusiak: Nepomuceno, Gabriella M., Chan, Katie M., Huynh, Valerie, Martin, Kevin S., Moore, Jared T., O’Brien, Terrence E., Pollo, Luiz A. E., Sarabia, Francisco J., Tadeus, Clarissa, Yao, Zi, Anderson, David E., Ames, James B., Shaw, Jared T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2015
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360151/
https://ncbi.nlm.nih.gov/pubmed/25815151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500497s
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