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RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment

RAGE is a multi-functional receptor implicated in diverse processes including inflammation and cancer. In this study, we report that RAGE expression is upregulated widely in aggressive triple-negative breast cancer cells, both in primary tumors and lymph node metastases. In evaluating the functional...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Nasser, Mohd W., Wani, Nissar Ahmad, Ahirwar, Dinesh K., Powell, Catherine A., Ravi, Janani, Elbaz, Mohamad, Zhao, Helong, Padilla, Laura, Zhang, Xiaoli, Shilo, Konstantin, Ostrowski, Michael, Shapiro, Charles, Carson, William E., Ganju, Ramesh K.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359968/
https://ncbi.nlm.nih.gov/pubmed/25572331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2161
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