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RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment

RAGE is a multi-functional receptor implicated in diverse processes including inflammation and cancer. In this study, we report that RAGE expression is upregulated widely in aggressive triple-negative breast cancer cells, both in primary tumors and lymph node metastases. In evaluating the functional...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Nasser, Mohd W., Wani, Nissar Ahmad, Ahirwar, Dinesh K., Powell, Catherine A., Ravi, Janani, Elbaz, Mohamad, Zhao, Helong, Padilla, Laura, Zhang, Xiaoli, Shilo, Konstantin, Ostrowski, Michael, Shapiro, Charles, Carson, William E., Ganju, Ramesh K.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359968/
https://ncbi.nlm.nih.gov/pubmed/25572331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2161
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