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C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment

INTRODUCTION: Although C-X-C motif chemokine 12 (CXCL12) has been shown to bind to C-X-C chemokine receptor type 7 (CXCR7), the exact molecular mechanism regulations by CXCL12/CXCR7 axis in breast tumor growth and metastasis are not well understood. CXCR7 expression has been shown to be upregulated...

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Detalhes bibliográficos
Main Authors: Wani, Nissar Ahmad, Nasser, Mohd W, Ahirwar, Dinesh K, Zhao, Helong, Miao, Zhenhua, Shilo, Konstantin, Ganju, Ramesh K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076630/
https://ncbi.nlm.nih.gov/pubmed/24886617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3665
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