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Steroid sidestep: Evading androgen ablation by abiraterone
Tumor mechanisms of abiraterone resistance in clinical prostate cancer are not well-defined. Chen and colleagues report that a T878A androgen receptor mutation occurs in subset of patients progressing while receiving abiraterone, suggesting this may be a therapeutically exploitable mechanism of abir...
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| Udgivet i: | Clin Cancer Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359949/ https://ncbi.nlm.nih.gov/pubmed/25432158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2899 |
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