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Gain of HIF-1α under normoxia in cancer mediates immune adaptation through the AKT/ERK and VEGFA axes

PURPOSE: Adaptation to host immune surveillance is now recognized as a hallmark of cancer onset and progression, and represents an early, indispensable event in cancer evolution. This process of evolution is first instigated by an immune selection pressure imposed by natural host surveillance mechan...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Lee, Young-Ho, Bae, Hyun Cheol, Noh, Kyung Hee, Song, Kwon-Ho, Ye, Sang-kyu, Mao, Chih-Ping, Lee, Kyung-Mi, Wu, TC, Kim, Tae Woo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359944/
https://ncbi.nlm.nih.gov/pubmed/25589622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1979
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