Poxvirus Decapping Enzymes Enhance Virulence by Preventing the Accumulation of dsRNA and the Induction of Innate Antiviral Responses

Poxvirus replication involves synthesis of double stranded RNA (dsRNA), which can trigger antiviral responses by inducing phosphorylation-mediated activation of protein kinase R (PKR) and stimulating 2’5’-oligoadenylate synthetase (OAS). PKR inactivates the translation initiation factor eIF2α via ph...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Host Microbe
Egile Nagusiak: Liu, Shin-Wu, Katsafanas, George C., Liu, Ruikang, Wyatt, Linda S., Moss, Bernard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359750/
https://ncbi.nlm.nih.gov/pubmed/25766293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.02.002
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