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Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes

Varp (VPS9-ankyrin repeat protein) was originally identified as an activator of small GTPase Rab21 through its VPS9 domain, but it has subsequently been shown to function as a Rab32/38 effector through its first ANKR1 domain. Although these functions of Varp are important for melanogenesis, Varp con...

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Vydáno v:Biol Open
Hlavní autoři: Yatsu, Ayaka, Shimada, Hikaru, Ohbayashi, Norihiko, Fukuda, Mitsunori
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359733/
https://ncbi.nlm.nih.gov/pubmed/25661869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201411114
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