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Zygotic Genome Activation Triggers the DNA Replication Checkpoint at the Midblastula Transition
A conserved feature of the midblastula transition (MBT) is a requirement for a functional DNA replication checkpoint to coordinate cell cycle remodeling and zygotic genome activation (ZGA). We have investigated what triggers this checkpoint during Drosophila embryogenesis. We find that the magnitude...
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| Veröffentlicht in: | Cell |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359640/ https://ncbi.nlm.nih.gov/pubmed/25748651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.050 |
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