Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination

Chronic demyelination is a pathological hallmark of multiple sclerosis (MS). Only a minority of MS lesions remyelinates completely. Enhancing remyelination is, therefore, a major aim of future MS therapies. Here we took a novel approach to identify factors that may inhibit or support endogenous remy...

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Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: Mohan, Hema, Friese, Anita, Albrecht, Stefanie, Krumbholz, Markus, Elliott, Christina L, Arthur, Ariel, Menon, Ramesh, Farina, Cinthia, Junker, Andreas, Stadelmann, Christine, Barnett, Susan C, Huitinga, Inge, Wekerle, Hartmut, Hohlfeld, Reinhard, Lassmann, Hans, Kuhlmann, Tanja, Linington, Chris, Meinl, Edgar
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359505/
https://ncbi.nlm.nih.gov/pubmed/25589163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0168-9
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