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Multiple sclerosis: Comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells

Copolymer 1 (COP), a standardized mixture of synthetic polypeptides consisting of l-glutamic acid, l-lysine, l-alanine, and l-tyrosine, has beneficial effects in multiple sclerosis and experimental autoimmune encephalomyelitis. We selected a panel of 721 COP-reactive T cell lines (TCL) from the bloo...

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Detalhes bibliográficos
Main Authors: Neuhaus, Oliver, Farina, Cinthia, Yassouridis, Alexander, Wiendl, Heinz, Then Bergh, Florian, Dose, Tatjana, Wekerle, Hartmut, Hohlfeld, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16566/
https://ncbi.nlm.nih.gov/pubmed/10861011
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